Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.70 |
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222984 | 0.95 | CNR2 (0.72) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7224493 | 0.91 | CNR2 (0.74) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7222291 | 0.90 | CNR2 (0.73) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7224225 | 0.90 | CNR2 (0.72) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7218990 | 0.89 | CNR2 (0.77) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7217327 | 0.88 | CNR2 (0.68) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7221735 | 0.88 | CNR2 (0.72) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7217548 | 0.87 | CNR2 (0.79) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7223681 | 0.87 | CNR2 (0.75) | CNR2CNR1KMT2AMEN1KDM4E | |
| SCHEMBL7222333 | 0.86 | CNR2 (0.72) | CNR2CNR1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653304-B2 | Antiarthritic agents; skin disorders; anticarcinogenic agents | BRISTOL-MYERS SQUIBB CO. | 2003-11-25 | — | — | US | disclosed |