Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217431 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 | |
| SCHEMBL7223596 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 | |
| SCHEMBL7225429 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNANLRP3NAMPT | |
| SCHEMBL7223685 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 | |
| SCHEMBL7223947 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNANLRP3HTT | |
| SCHEMBL27261071 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 | |
| SCHEMBL7219387 | 0.80 | MEN1 (0.43) | SMN1; SMN2ALDH1A1LMNANLRP3HTT | |
| SCHEMBL7225295 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2LMNANLRP3HTTMAPT | |
| SCHEMBL7223600 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 | |
| SCHEMBL7223939 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNANLRP3CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |