Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.43 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7250157 | 0.80 | F2 (0.65) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL6985099 | 0.78 | F2 (0.63) | F2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6161320 | 0.78 | F2 (0.53) | F2NPC1RAB9ANTRK1NTRK2 | |
| SCHEMBL7252982 | 0.77 | F2 (0.68) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7251642 | 0.76 | F2 (0.67) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7216966 | 0.76 | F2 (0.53) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7253337 | 0.76 | F2 (0.64) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7484192 | 0.75 | F2 (0.50) | F2NPC1RAB9ANTRK1NTRK2 | |
| Hydrochloric Acid SCHEMBL7430334 | 0.74 | F2 (0.59) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL6635045 | 0.74 | F2 (0.60) | F2SLC22A2F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |