SCHEMBL722381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723929	0.89	PIM1 (0.50)	RPS6KA3JAK2ACVR1BTGFBR1BMPR1B
	SCHEMBL723388	0.89	KDM4E (0.51)	PRKDCPIK3CAPIK3CBPIK3CGJAK2
	SCHEMBL724754	0.89	CNR2 (0.47)	PRKDCPIK3CAPIK3CBPIK3CGLRRK2
	SCHEMBL723621	0.82	MAPK10 (0.51)	LRRK2PIK3R2MAPK10ACVR1BTGFBR1
	SCHEMBL724726	0.78	CNR2 (0.50)	PIK3CBATR
	SCHEMBL15209104	0.78	MAPKAPK2 (0.48)	RPS6KA3CHEK1ACVR1BTGFBR1BMPR1B
	SCHEMBL723758	0.78	DYRK1A (0.47)	DYRK1APIK3CALRRK2CHEK1KDR
	SCHEMBL722890	0.78	PRKDC (0.48)	PRKDCMAPK10ACVR1BTGFBR1BMPR1B
	SCHEMBL723599	0.76	PIK3CA (0.43)	PIK3CA
	SCHEMBL725108	0.76	KDR (0.54)	JAK3KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.