Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.60 |
| ▸ | CNR1 | P21554 | 4/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218941 | 0.90 | CNR2 (0.62) | CNR2CNR1ITGA4ITGB7ITGB1 | |
| SCHEMBL7223438 | 0.86 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL7224514 | 0.85 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL7224453 | 0.84 | CNR2 (0.73) | CNR2CNR1 | |
| SCHEMBL7641363 | 0.83 | CNR2 (0.69) | CNR2CNR1ITGA4ITGB7ITGB1 | |
| SCHEMBL7223428 | 0.82 | CNR2 (0.67) | CNR2CNR1ITGA4ITGB7ITGB1 | |
| SCHEMBL7216870 | 0.82 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL7223586 | 0.82 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL7223587 | 0.81 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL7223599 | 0.81 | CNR2 (0.70) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653304-B2 | Antiarthritic agents; skin disorders; anticarcinogenic agents | BRISTOL-MYERS SQUIBB CO. | 2003-11-25 | — | — | US | disclosed |