Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 9/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6474657 | 0.99 | HTR2A (0.51) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| SCHEMBL6475429 | 0.83 | HTR2A (0.53) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| SCHEMBL6475068 | 0.83 | HTR2A (0.53) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| SCHEMBL6475419 | 0.82 | HTR2A (0.55) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| SCHEMBL7227445 | 0.82 | HTR2C (0.49) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| Hydrochloric Acid SCHEMBL6474628 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7TAAR1KDM4E | |
| Hydrochloric Acid SCHEMBL6476137 | 0.81 | CYP1A2 (0.44) | HTR2AHTR2CHTR7TAAR1NISCH | |
| Hydrochloric Acid SCHEMBL6473408 | 0.81 | HTR2C (0.48) | HTR2AHTR2CHTR7TAAR1PARP1 | |
| Hydrochloric Acid SCHEMBL6474048 | 0.81 | HTR2A (0.57) | HTR2AHTR2CTAAR1KDM4EHTR5A | |
| SCHEMBL6475897 | 0.80 | HTR2A (0.47) | HTR2AHTR2CHTR7TAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583135-B2 | Treating central nervous system disorders wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity). | PHARMACIA & UPJOHN COMPANY | 2003-06-24 | — | — | US | disclosed |