Phenylalanine

Phenylalanine

SCHEMBL7226502

N[C@@H](Cc1ccccc1)C(=O)O.[NaH].[NaH]

nearest known ligand 0.96

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.96
PTGS1 P23219 2/20 0.96
ALPI P09923 1/20 0.96
PKM P14618 1/20 0.96
XIAP P98170 1/20 0.96
SLC1A3 P43003 2/20 0.67
SLC1A2 P43004 2/20 0.67
SLC1A1 P43005 2/20 0.67
SLC15A1 P46059 1/20 0.61
CYP1A2 P05177 1/20 0.59
LTA4H P09960 1/20 0.58
GRIA2 P42262 1/20 0.57
KDM4E B2RXH2 1/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
ALOX15 P16050 1/20 0.56
HTR2A P28223 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Phenylalanine SCHEMBL22656002 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL28899613 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL2584996 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL6005348 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
D-Phenylalanine SCHEMBL28862316 0.98 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL10931123 0.98 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL10931112 0.98 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL10933973 0.98 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL10933984 0.98 SLC7A5 (0.92) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23159186 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115414421-A Extraction method and application of cortex dictamni active ingredients 上海川跃生物科技有限公司 2022-12-02 CN disclosed
US-6596752-B1 Small molecules that are potent inhibitors of alpha 4 beta 1 mediated adhesion to either VCAM or CS-1 and which could be useful for the treatment of inflammatory diseases. TANABE SEIYAKU CO., LTD. (JP) 2003-07-22 US disclosed
US-6482849-B1 Inhibitors of α4β1 mediated cell adhesion TANABE SEIYAKU CO., LTD. (JP) 2002-11-19 US disclosed