Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 10/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233388 | 0.97 | PARP14 (1.00) | PARP14TSHRKDM4EHPGDSBCHE | |
| SCHEMBL6631009 | 0.96 | PARP14 (0.98) | PARP14TSHRKDM4EHPGDSBCHE | |
| SCHEMBL6616823 | 0.81 | PARP14 (0.65) | PARP14HPGDSBCHEMAPK1HSD17B10 | |
| SCHEMBL7097307 | 0.81 | PARP14 (0.65) | PARP14TSHRHPGDSBCHEMAPK1 | |
| Hydrochloric Acid SCHEMBL7477351 | 0.81 | PARP14 (0.65) | PARP14TSHRHPGDSBCHEMAPK1 | |
| SCHEMBL6633296 | 0.81 | PARP14 (0.93) | PARP14HPGDSBCHEMAPK1CHRM2 | |
| SCHEMBL6631323 | 0.81 | PARP14 (0.65) | PARP14HPGDSBCHEMAPK1HSD17B10 | |
| SCHEMBL6634683 | 0.81 | PARP14 (0.64) | PARP14HPGDSBCHEMAPK1HSD17B10 | |
| SCHEMBL5390600 | 0.80 | PARP14 (0.64) | PARP14HPGDSBCHEMAPK1HSD17B10 | |
| SCHEMBL7235615 | 0.80 | PARP14 (0.64) | PARP14HPGDSBCHEMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610694-B1 | Suppressing histamine and/or eosinophil chemotaxis; treating allergic diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1120418-A1 | FUSED PYRIDAZINE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |