Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771069 | 0.80 | KDM4E (0.54) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL4037331 | 0.77 | KDM4E (0.69) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL7486859 | 0.76 | KDM4E (0.57) | KDM4EPPARAPPARGHRH3FFAR1 | |
| SCHEMBL6776301 | 0.76 | KDM4E (0.53) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL6780817 | 0.76 | KDM4E (0.50) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL6780825 | 0.76 | KDM4E (0.50) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL6770398 | 0.75 | KDM4E (0.55) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL7247822 | 0.75 | KDM4E (0.55) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL7247816 | 0.75 | KDM4E (0.55) | KDM4EHPGDRAB9ANPC1PPARA | |
| SCHEMBL6773338 | 0.75 | KDM4E (0.49) | KDM4EHPGDRAB9ANPC1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589969-B1 | A peroxisome proliferator activated receptor regulator containing a compound of formula (I) Because of having an effect of regulating PPAR, a compound of formula (I) is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1122255-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |