SCHEMBL722880

SCHEMBL722880

C=CN1CCC([SiH3])C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860099 0.78
SCHEMBL10349558 0.74
SCHEMBL1155614 0.74
SCHEMBL195053 0.74
SCHEMBL8658305 0.74
SCHEMBL2877520 0.74
SCHEMBL7082100 0.74
SCHEMBL5762435 0.74
SCHEMBL5576883 0.74
SCHEMBL10783643 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3061470-B1 METAL MEDICAL DEVICE HAVING LUBRICITY AND LOW PROTEIN ADSORPTION PROPERTIES AND/OR LOW CELL ADSORPTION PROPERTIES, AND METHOD FOR PRODUCING SAME SUMITOMO RUBBER IND (JP) 2020-12-16 EP disclosed
EP-2519270-B1 SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES SURMODICS INC (US) 2017-02-15 EP disclosed
US-8475843-B2 Silyl ether-modified hydrophilic polymers and uses for medical articles SURMODICS, INC. (US) 2013-07-02 US disclosed
EP-2519270-A1 SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES SurModics, Inc. (US) 2012-11-07 EP disclosed
US-20120052123-A9 SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES Surmodics Coatings, LLC 2012-03-01 US disclosed
WO-2011082296-A1 SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES SURMODICS, INC. (US) 2011-07-07 WO disclosed
US-20110159101-A1 SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES BANK OF MONTREAL, AS COLLATERAL AGENT 2011-06-30 US disclosed