Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.57 |
| ▸ | ESR1 | P03372 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betanaphthol SCHEMBL10436099 | 0.98 | CYP1A2 (0.81) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL27717167 | 0.91 | CYP1A2 (0.77) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL8651479 | 0.91 | CYP1A2 (0.94) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Anthracene SCHEMBL28283702 | 0.88 | CYP1A2 (0.90) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL27598725 | 0.88 | CYP1A2 (0.90) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL28781 | 0.88 | CYP1A2 (1.00) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL29658180 | 0.88 | CYP1A2 (1.00) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL11594695 | 0.88 | CYP1A2 (1.00) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL239472 | 0.88 | CYP1A2 (1.00) | CYP1A2ESR2ESR1MEN1NPC1 | |
| Betanaphthol SCHEMBL7963622 | 0.88 | CYP1A2 (0.65) | CYP1A2ESR2ESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627121-B1 | Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-09-30 | — | — | US | disclosed |
| WO-2001010858-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2001-02-15 | — | — | WO | disclosed |