Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 11/20 | 0.56 |
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186803 | 0.78 | CYP1A2 (0.43) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL30944686 | 0.78 | ESR2 (0.81) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL5302383 | 0.78 | ESR2 (0.81) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL29506882 | 0.78 | ESR2 (0.81) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL11430028 | 0.78 | ESR2 (0.65) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL682421 | 0.77 | KMT2A (0.55) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL5426888 | 0.76 | ESR1 (0.90) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL30186239 | 0.75 | PTPN22 (0.57) | CYP1A2CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL19501075 | 0.75 | ESR2 (0.77) | ESR2ESR1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL3927764 | 0.75 | ESR2 (0.77) | ESR2ESR1HSD17B1HSD17B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627121-B1 | Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-09-30 | — | — | US | disclosed |
| WO-2001010858-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2001-02-15 | — | — | WO | disclosed |