Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 15/20 | 0.76 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870484 | 0.86 | PDGFRB (1.00) | PDGFRBPDGFRAFGFR1FLT3PRKCE | |
| SCHEMBL5716684 | 0.82 | PDGFRB (0.64) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL10646484 | 0.81 | PDGFRB (0.53) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL5716749 | 0.80 | PDGFRB (0.72) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL2729915 | 0.79 | FLT3 (0.79) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL15558759 | 0.78 | FLT3 (0.71) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL7066259 | 0.78 | FLT3 (0.71) | PDGFRBPDGFRAFGFR1FLT3HDAC6 | |
| SCHEMBL19307573 | 0.78 | MAOB (0.62) | PDGFRBPDGFRAKMT2A | |
| SCHEMBL19307571 | 0.78 | MAOB (0.62) | PDGFRBPDGFRAKMT2A | |
| SCHEMBL6168456 | 0.77 | MEN1 (0.70) | PDGFRBPDGFRAFGFR1FLT3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548505-B1 | Protecting biological materials from damage caused by radiation; side effect reduction during radiotherapy or chemotherapy; indole, benzimidazole, benzoxazole or benzothiazole compounds substituted with 4-alkylpiperazino | PETER MACCALLUM CANCER INSTITUTE (AU) | 2003-04-15 | — | — | US | disclosed |