Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198560 | 0.86 | POLB (0.56) | SMN1; SMN2HTTRAB9ANPC1KMT2A | |
| SCHEMBL31306634 | 0.86 | POLB (0.56) | SMN1; SMN2HTTRAB9ANPC1KMT2A | |
| SCHEMBL27519915 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL27546668 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL27546578 | 0.85 | NPC1 (0.56) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL7436440 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL7434461 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL14015952 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL28745974 | 0.83 | GAA (0.79) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL21197934 | 0.83 | ANO1 (0.63) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602987-B1 | 4'-hydroxyazobenzene-2-carboxylic acid (HABA) compounds; useful as reagents for labeling, isolation and detection of biological molecules | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-08-05 | — | — | US | disclosed |