Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 5/20 | 0.31 |
| ▸ | ACACA | Q13085 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232668 | 0.95 | TDP1 (0.39) | BTKTDP1KMT2AMEN1GAA | |
| SCHEMBL7230514 | 0.90 | BTK (0.37) | BTKTDP1KMT2AMEN1GAA | |
| SCHEMBL7230862 | 0.90 | BTK (0.37) | BTKTDP1KMT2AMEN1GAA | |
| SCHEMBL7232725 | 0.85 | BTK (0.34) | BTKTDP1KMT2AMEN1GAA | |
| SCHEMBL7230501 | 0.84 | EPHX1 (0.36) | BTKTDP1KMT2AMEN1GAA | |
| SCHEMBL7235646 | 0.81 | BTK (0.44) | BTKKMT2AGAAEPHX1CTSS | |
| SCHEMBL7232715 | 0.80 | KMT2A (0.34) | TDP1KMT2AMEN1GAAEPHX1 | |
| SCHEMBL7238417 | 0.77 | BTK (0.40) | BTKKMT2AEPHX1CTSSCTSK | |
| SCHEMBL7231122 | 0.77 | BTK (0.40) | BTKKMT2AEPHX1CTSSCTSK | |
| SCHEMBL7235642 | 0.76 | BTK (0.38) | BTKTDP1KMT2AGAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518305-B1 | For inhibiting neuraminidases from disease- causing microorganisms, especially, influenza neuraminidase | ABBOTT LABORATORIES | 2003-02-11 | — | — | US | disclosed |