Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 11/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239081 | 0.95 | FDFT1 (0.45) | FDFT1 | |
| SCHEMBL7238804 | 0.93 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL7236311 | 0.92 | FDFT1 (0.53) | FDFT1HCRTR1HCRTR2 | |
| SCHEMBL7239836 | 0.90 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL7240963 | 0.89 | FDFT1 (0.55) | FDFT1 | |
| SCHEMBL7236615 | 0.88 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL7236599 | 0.88 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL7241816 | 0.88 | FDFT1 (0.45) | FDFT1 | |
| SCHEMBL7235973 | 0.88 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL7238204 | 0.87 | FDFT1 (0.53) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6537987-B1 | This invention relates to certain benzoxazepinones and benzothiazepinones useful as hypocholesterolemic agents, hypotriglyceridemic agents, antiatherosclerosis agents, antifungal agents, anti-Alzheimer's agents or anti-acne | PFIZER INC. | 2003-03-25 | — | — | US | claimed |
| WO-1997048701-A1 | 4,1-BENZOXAZEPINES OR 4,1-BENZOTHIAZEPINES AND THEIR USE AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1997-12-24 | — | — | WO | claimed |
| US-6537987-B1 | This invention relates to certain benzoxazepinones and benzothiazepinones useful as hypocholesterolemic agents, hypotriglyceridemic agents, antiatherosclerosis agents, antifungal agents, anti-Alzheimer's agents or anti-acne | PFIZER INC. | 2003-03-25 | — | — | US | disclosed |