Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15839353 | 0.90 | TAAR1 (0.57) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL27721818 | 0.90 | BCHE (0.49) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL31267723 | 0.90 | BCHE (0.49) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL15432648 | 0.90 | CYP4F2 (0.61) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL22215905 | 0.89 | KDM4E (0.51) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL2318952 | 0.87 | KDM4E (0.50) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL9203324 | 0.87 | CYP4F2 (0.50) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL1520719 | 0.86 | MEN1 (0.50) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL13993806 | 0.85 | CHRM2 (0.62) | BCHEKDM4ENPC1RAB9AGAA | |
| SCHEMBL2522114 | 0.85 | KDM4E (0.52) | BCHEKDM4ENPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | claimed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | claimed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | claimed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | claimed |
| US-8541625-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | BCHE 2152/4885KDM4E 3772/4885NPC1 4164/4885 |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | BCHE 2152/4885KDM4E 3772/4885NPC1 4164/4885 |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | BCHE 2152/4885KDM4E 3772/4885NPC1 4164/4885 |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | BCHE 2152/4885KDM4E 3772/4885NPC1 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.