Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723568 | 1.00 | HDAC1 (0.64) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL27741238 | 0.92 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1481640 | 0.92 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1481642 | 0.92 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL723534 | 0.87 | CHRM1 (0.66) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL723533 | 0.87 | CHRM1 (0.66) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL724056 | 0.86 | HDAC1 (0.69) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL723773 | 0.86 | HDAC1 (0.67) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1486886 | 0.86 | HDAC1 (0.69) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL723772 | 0.86 | HDAC1 (0.67) | HDAC1HDAC6HDAC8HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025155-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | disclosed |