Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 4/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MTR | Q99707 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241861 | 0.98 | MTTP (0.52) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7238229 | 0.96 | MTTP (0.53) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7241754 | 0.95 | MTTP (0.50) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7232988 | 0.94 | MTTP (0.52) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7240365 | 0.94 | MTTP (0.55) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7241468 | 0.93 | MTTP (0.51) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7238588 | 0.93 | MTTP (0.51) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7237776 | 0.93 | MTTP (0.54) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7239680 | 0.93 | MTTP (0.51) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7233468 | 0.93 | MTTP (0.53) | MTTPCHRM2ADRA2AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617325-B1 | Inhibitors of the microsomal triglyceride-transfer protein | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-09 | — | — | US | disclosed |