Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.95 |
| ▸ | ATM | Q13315 | 1/20 | 0.95 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19355275 | 0.97 | TAAR1 (1.00) | TAAR1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL1878 | 0.97 | TAAR1 (1.00) | TAAR1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL27896457 | 0.95 | TAAR1 (0.95) | TAAR1ATML3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1696934 | 0.95 | TAAR1 (0.95) | TAAR1ATML3MBTL1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL19693169 | 0.95 | TAAR1 (0.95) | TAAR1ATML3MBTL1MEN1KMT2A | |
| Fluoride Ion SCHEMBL28826041 | 0.93 | TAAR1 (0.91) | TAAR1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL28826039 | 0.91 | TAAR1 (0.86) | TAAR1ATML3MBTL1MEN1KMT2A | |
| Diethylamine SCHEMBL7488588 | 0.87 | TAAR1 (0.79) | TAAR1ATML3MBTL1MEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL8723500 | 0.87 | TAAR1 (0.79) | TAAR1ATML3MBTL1MEN1KMT2A | |
| Formic Acid SCHEMBL3537931 | 0.85 | TAAR1 (0.76) | TAAR1ATML3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645989-B2 | Antiinflammatory agents | SMITHKLINE BEECHAM CORPORATION | 2003-11-11 | — | — | US | disclosed |
| US-20030064997-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION | 2003-04-03 | — | — | US | disclosed |
| US-6268370-B1 | CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-5916891-A | CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686455-A | Imidazole derivatives and their use as cytokine inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| US-5656644-A | CYTOKINE SUPPRESSORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064997-A1 | Novel compounds | BRD4, BRDT, HDAC6 | TAAR1 3160/4885ATM 1370/4885L3MBTL1 3052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.