SCHEMBL723675

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723954	0.96	AHR (0.47)	PIK3CDPIK3CAMTORNPC1AHR
	SCHEMBL725225	0.92	MAP3K11 (0.50)	NPC1CYP17A1CYP11B1CYP11B2MAP3K11
	SCHEMBL31256758	0.92	MAP3K11 (0.50)	NPC1CYP17A1CYP11B1CYP11B2MAP3K11
	SCHEMBL786541	0.83	NPC1 (0.44)	NPC1AHRGRIA1PDE3BPDE3A
	SCHEMBL724718	0.82	PDE3B (0.46)	PIK3CAMTORNPC1PDE3BPDE3A
	SCHEMBL856313	0.80	AHR (0.70)	PIK3CDPIK3CAMTORNPC1AHR
	SCHEMBL29895884	0.80	NPC1 (0.53)	NPC1AHRCYP17A1CYP11B1CYP11B2
	SCHEMBL17732364	0.79	MAP3K11 (0.40)	PIK3CDPIK3CAMTORNPC1CYP17A1
	SCHEMBL15151753	0.79	MAP3K11 (0.40)	PIK3CDPIK3CAMTORNPC1AHR
	SCHEMBL723823	0.79	MAP3K11 (0.59)	MAP3K11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.