SCHEMBL7238121

SCHEMBL7238121

CC(C)c1cc(OCCN2CCOCC2)cc2c1C(=O)N(COC(=O)c1ccc(Cl)cc1Cl)S2(=O)=O

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 18/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440256 0.89 ELANE (0.77) ELANE
SCHEMBL7305284 0.82 ELANE (1.00) ELANE
Hydrochloric Acid SCHEMBL7314311 0.81 ELANE (0.99) ELANE
SCHEMBL7239540 0.79 ELANE (0.61) ELANE
SCHEMBL7238914 0.79 ELANE (0.56) ELANE
SCHEMBL7436955 0.75 ELANE (1.00) ELANE
Hydrochloric Acid SCHEMBL7288631 0.74 ELANE (0.90) ELANE
Hydrochloric Acid SCHEMBL7298524 0.74 ELANE (0.70) ELANE
SCHEMBL7282216 0.74 ELANE (0.80) ELANE
SCHEMBL8830250 0.73 ELANE (0.79) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114449-A1 SACCHARIN DERIVATIVES AS ORALLY ACTIVE ELASTASE INHIBITORS SANOFI-SYNTHELABO (FR) 2003-06-19 US disclosed