Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HPSE | Q9Y251 | 14/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121567 | 0.82 | NPC1 (0.59) | GAAHPSEKDM4EALDH1A1 | |
| SCHEMBL3807350 | 0.81 | GAA (0.69) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL11626342 | 0.80 | HPSE (0.72) | GAAHPSEKDM4EALDH1A1 | |
| SCHEMBL506581 | 0.80 | GAA (0.67) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| Methane SCHEMBL505763 | 0.79 | HPSE (0.70) | GAAHPSEKDM4EALDH1A1 | |
| SCHEMBL3102305 | 0.79 | GAA (1.00) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| Methane SCHEMBL25304065 | 0.78 | HPSE (0.69) | HPSEKDM4EALDH1A1 | |
| SCHEMBL507169 | 0.78 | KDM4E (0.77) | GAAHPSEKDM4EALDH1A1 | |
| SCHEMBL7243392 | 0.78 | GAA (0.64) | GAAHPSEKDM4EMEN1ALDH1A1 | |
| SCHEMBL11636238 | 0.77 | HPSE (0.55) | GAAHPSEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544989-B2 | Fungicidal, insecticidal, acaricidal, molluscicidal or nematicidal composition | SYNGENTA LIMITED (GB) | 2003-04-08 | — | — | US | disclosed |
| EP-1100798-B1 | BENZAZOLE, BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | SYNGENTA LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| EP-1100798-A1 | BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | Zeneca Limited (GB) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006566-A1 | BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-02-10 | — | — | WO | disclosed |