Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234522 | 0.88 | KDR (0.73) | KDR | |
| SCHEMBL7227257 | 0.88 | KDR (0.77) | KDR | |
| SCHEMBL5742138 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL6179139 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL6179438 | 0.85 | KDR (1.00) | KDR | |
| SCHEMBL7230112 | 0.84 | KDR (0.69) | KDR | |
| SCHEMBL6178356 | 0.84 | KDR (0.74) | KDR | |
| SCHEMBL5742011 | 0.84 | KDR (1.00) | KDR | |
| SCHEMBL6177027 | 0.83 | KDR (1.00) | KDR | |
| SCHEMBL6178074 | 0.83 | KDR (1.00) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586424-B2 | Anticancer agents; anticholesterol agents | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |
| US-6586423-B2 | 2-(Pyridin-2-ylamino)-thiazole-5-carbonitrile derivatives; angiogenesis inhibitors; antitumor and anticarcinogenic agents; atherosclerosis, macular degeneration, diabetic retinopathy | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |