Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | KYNU | Q16719 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594070 | 0.78 | TYR (0.48) | TYRLMNAKDM4E | |
| SCHEMBL7245770 | 0.77 | TYR (0.47) | TYRMEN1KMT2A | |
| SCHEMBL7261616 | 0.75 | MEN1 (0.47) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL7262096 | 0.75 | MEN1 (0.43) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL6454550 | 0.75 | TYR (0.47) | TYRLMNAKDM4E | |
| SCHEMBL6451064 | 0.75 | TYR (0.47) | TYRLMNAKDM4E | |
| SCHEMBL6451059 | 0.75 | TYR (0.47) | TYRLMNAKDM4E | |
| SCHEMBL2471893 | 0.73 | TYR (0.49) | TYR | |
| SCHEMBL2477921 | 0.73 | TYR (0.49) | TYR | |
| SCHEMBL2471896 | 0.73 | TYR (0.49) | TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541473-B2 | Use as skin lightening agents; 4-(1,4-Dioxaspiro(4.5)dec-8-yl)-1,3-benzenediol for example | WARNER LAMBERT COMPANY | 2003-04-01 | — | — | US | disclosed |