Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216699 | 0.85 | PIM1 (0.46) | PIM1PIM2CHRM5TAAR1FURIN | |
| SCHEMBL2849892 | 0.84 | PIM1 (0.49) | PIM1PIM2MAPTHTTCHRM5 | |
| SCHEMBL2849894 | 0.84 | PIM1 (0.49) | PIM1PIM2MAPTHTTCHRM5 | |
| SCHEMBL13322138 | 0.84 | PIM1 (0.49) | PIM1PIM2MAPTHTTCHRM5 | |
| SCHEMBL10664352 | 0.80 | PTGES2 (0.43) | PIM1PIM2MAPTHTTFURIN | |
| SCHEMBL896842 | 0.79 | PIM1 (0.56) | PIM1PIM2MAPTHTTEPHX2 | |
| SCHEMBL19595301 | 0.79 | PIM1 (0.52) | PIM1PIM2MAPTHTTABL1 | |
| SCHEMBL498326 | 0.77 | PIM1 (0.48) | PIM1PIM2MAPTABL1BCR | |
| SCHEMBL7237043 | 0.74 | GCGR (0.48) | MAPT | |
| SCHEMBL1560 | 0.73 | CYP3A4 (0.48) | PIM1PIM2MAPTABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |