Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240541 | 0.84 | MCL1 (0.49) | — | |
| SCHEMBL7239430 | 0.83 | MCL1 (0.42) | — | |
| SCHEMBL7238527 | 0.83 | CHEK1 (0.36) | CHEK1WEE1SMN1; SMN2 | |
| SCHEMBL7241215 | 0.80 | MCL1 (0.42) | MAOASMN1; SMN2 | |
| SCHEMBL7237841 | 0.80 | MCL1 (0.39) | — | |
| SCHEMBL7240115 | 0.79 | ALOX5AP (0.34) | CHEK1WEE1 | |
| SCHEMBL7240113 | 0.79 | ALOX5AP (0.34) | CHEK1WEE1 | |
| SCHEMBL7237631 | 0.79 | MCL1 (0.44) | — | |
| SCHEMBL7238919 | 0.78 | CNR2 (0.42) | — | |
| SCHEMBL7240554 | 0.78 | SMN1; SMN2 (0.34) | CHEK1WEE1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608059-B1 | Treating bacterial infections | SMITHKLINE BEECHAM CORPORATION | 2003-08-19 | — | — | US | disclosed |