⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238996 | 0.89 | — | — | |
| SCHEMBL8184161 | 0.76 | — | — | |
| SCHEMBL8187363 | 0.75 | — | — | |
| SCHEMBL3903690 | 0.72 | — | — | |
| SCHEMBL9405181 | 0.69 | — | — | |
| SCHEMBL8182556 | 0.69 | — | — | |
| Chloromethane SCHEMBL3670008 | 0.69 | — | — | |
| SCHEMBL8183373 | 0.68 | — | — | |
| SCHEMBL5947696 | 0.68 | — | — | |
| SCHEMBL7149929 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | claimed |
| WO-2002078695-A1 | THIAPORPHYRIN, SELENAPORPHYRIN, AND CAROTENOID PORPHYRIN COMPOUNDS AS C-MYC AND TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-10-10 | — | — | WO | claimed |
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | disclosed |