Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 18/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113577 | 0.96 | FDFT1 (0.88) | FDFT1 | |
| Lapaquistat Acetate SCHEMBL8007641 | 0.94 | FDFT1 (1.00) | FDFT1 | |
| Lapaquistat Acetate SCHEMBL29395209 | 0.94 | FDFT1 (1.00) | FDFT1 | |
| Lapaquistat Acetate SCHEMBL12882274 | 0.94 | FDFT1 (1.00) | FDFT1 | |
| Lapaquistat Acetate SCHEMBL29379346 | 0.94 | FDFT1 (1.00) | FDFT1 | |
| Lapaquistat Acetate SCHEMBL206424 | 0.94 | FDFT1 (1.00) | FDFT1 | |
| SCHEMBL14377991 | 0.94 | FDFT1 (0.99) | FDFT1 | |
| SCHEMBL14377992 | 0.93 | FDFT1 (0.95) | FDFT1 | |
| SCHEMBL14539358 | 0.92 | FDFT1 (0.79) | FDFT1 | |
| SCHEMBL4110712 | 0.91 | FDFT1 (0.81) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613761-B1 | (3R,5S)-N- methanesulfonyl-7-chloro-5-(2,3-dimethoxyphenyl) -1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4, 1-benzoxazepine-3-acetamide, used as antilipemic agents and enzyme inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-02 | — | — | US | disclosed |