Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303531 | 0.90 | PTPN1 (0.68) | PTPN1CDC25BPTPRCCDC25ACES2 | |
| SCHEMBL24597737 | 0.81 | PTPN1 (0.51) | PTPN1CDC25BALDH1A1CDC25ALTB4R | |
| SCHEMBL7239675 | 0.79 | PTPN1 (0.56) | PTPN1CDC25BPTPRCCES2CES1 | |
| SCHEMBL4298282 | 0.78 | PTPN1 (0.67) | PTPN1CDC25BPTPRCALDH1A1CES2 | |
| SCHEMBL7484901 | 0.78 | CDC25B (0.41) | PTPN1CDC25BPTPRCALDH1A1CDC25A | |
| SCHEMBL5596353 | 0.77 | PTPN1 (0.68) | PTPN1CDC25BPTPRCALDH1A1CDC25A | |
| SCHEMBL5595788 | 0.76 | PTPN1 (0.68) | PTPN1CDC25BPTPRCALDH1A1CDC25A | |
| SCHEMBL4291302 | 0.76 | PTPN1 (0.88) | PTPN1CDC25BPTPRCALDH1A1CES2 | |
| SCHEMBL4289068 | 0.76 | PTPN1 (0.68) | PTPN1CDC25BPTPRCCES2CES1 | |
| SCHEMBL4289513 | 0.76 | PTPN1 (0.56) | PTPN1CDC25BPTPRCCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649587-B1 | Cytostatic or cytocidal componenet conjugated to a polypeptide recognized and cleaved by enzymes such as prostate specific antigen (PSA) and cathepsin B | SLIL BIOMEDICAL CORPORATION | 2003-11-18 | — | — | US | disclosed |