Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243628 | 0.92 | CAPN1 (0.64) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7241206 | 0.91 | CHIA (0.59) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7242743 | 0.90 | TSHR (0.54) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7241988 | 0.89 | CAPN1 (0.59) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7243112 | 0.88 | TSHR (0.55) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7233171 | 0.87 | CAPN1 (0.57) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7235671 | 0.87 | TSHR (0.52) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7234715 | 0.85 | TSHR (0.49) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7232927 | 0.85 | CAPN1 (0.54) | HSD17B10TSHRCAPN1CTSSCHIA | |
| SCHEMBL7243638 | 0.83 | TSHR (0.57) | HSD17B10TSHRCAPN1CTSSATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562827-B1 | For the treatment of diseases in which increased calpain activity occurs such as neurodegenerative diseases or neuronal damage are caused by ischemia, trauma or mass hemorrhages | ABBOTT LABORATORIES | 2003-05-13 | — | — | US | disclosed |