Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 10/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7240413 | 0.99 | GRM1 (0.66) | GRM1ALDH1A1HPGDMAPTITK | |
| SCHEMBL7240196 | 0.93 | GRM1 (0.77) | GRM1ALDH1A1HPGDMAPTITK | |
| Hydrochloric Acid SCHEMBL7240402 | 0.92 | GRM1 (0.76) | GRM1ALDH1A1HPGDMAPTITK | |
| SCHEMBL658904 | 0.87 | GRM1 (0.87) | GRM1ALDH1A1HPGDMAPTITK | |
| Hydrochloric Acid SCHEMBL7232011 | 0.86 | GRM1 (0.62) | GRM1ALDH1A1HPGDMAPTITK | |
| Hydrochloric Acid SCHEMBL7233125 | 0.85 | GRM1 (0.61) | GRM1ALDH1A1HPGDMAPTITK | |
| SCHEMBL7234060 | 0.83 | GRM1 (0.79) | GRM1ALDH1A1HPGDMAPTITK | |
| Hydrochloric Acid SCHEMBL7240881 | 0.83 | GRM1 (0.78) | GRM1ALDH1A1HPGDMAPTITK | |
| SCHEMBL7237522 | 0.81 | GRM1 (0.56) | GRM1ALDH1A1HPGDMAPTITK | |
| Hydrochloric Acid SCHEMBL7235509 | 0.80 | MAPT (0.58) | GRM1ALDH1A1HPGDMAPTITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | claimed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | claimed |
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |