Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 2/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | EIF4E | P06730 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925297 | 0.88 | C1S (0.54) | C1SPLAUEIF4EMAPTRAB9A | |
| SCHEMBL6919970 | 0.85 | C1S (0.60) | C1SPLAUEIF4EMAPTRAB9A | |
| SCHEMBL6924874 | 0.84 | C1S (0.60) | C1SPLAUEIF4EMAPTMEN1 | |
| SCHEMBL6925339 | 0.81 | PLAU (0.56) | C1SPLAUMAPTRAB9AMEN1 | |
| SCHEMBL6921101 | 0.77 | C1S (0.60) | C1SPLAUMAPTMEN1KMT2A | |
| SCHEMBL6927972 | 0.76 | C1S (0.78) | C1SPLAUEIF4EMAPTRAB9A | |
| SCHEMBL6927280 | 0.75 | C1S (0.58) | C1SPLAUEIF4EMAPTRAB9A | |
| SCHEMBL28521847 | 0.74 | MAPT (0.65) | EIF4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL6920039 | 0.74 | C1S (0.57) | C1SPLAUEIF4EMAPTMEN1 | |
| SCHEMBL27574705 | 0.73 | C1S (0.73) | C1SPLAUEIF4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |