Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929070 | 0.90 | PLAU (0.73) | PLAU | |
| Hydrochloric Acid SCHEMBL6926765 | 0.89 | PLAU (0.72) | PLAU | |
| SCHEMBL6924830 | 0.87 | PLAU (1.00) | PLAU | |
| Hydrochloric Acid SCHEMBL6924903 | 0.87 | PLAU (0.98) | PLAU | |
| SCHEMBL6928777 | 0.86 | PLAU (1.00) | PLAU | |
| SCHEMBL6920841 | 0.85 | PLAU (1.00) | PLAU | |
| SCHEMBL6926957 | 0.85 | PLAU (1.00) | PLAU | |
| Hydrochloric Acid SCHEMBL6926764 | 0.85 | PLAU (0.98) | PLAU | |
| Hydrochloric Acid SCHEMBL6925705 | 0.85 | PLAU (0.98) | PLAU | |
| Hydrochloric Acid SCHEMBL6924685 | 0.85 | PLAU (0.98) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |