Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7248266 | 0.99 | FFAR1 (0.48) | FFAR1PPARGPPARAALDH1A1NPSR1 | |
| SCHEMBL1130792 | 0.90 | PPARG (0.54) | FFAR1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL6701459 | 0.89 | PPARG (0.47) | FFAR1PPARGPPARACYP3A4 | |
| Hydrochloric Acid SCHEMBL6064786 | 0.89 | PPARG (0.53) | FFAR1PPARGPPARACYP3A4 | |
| Hydrochloric Acid SCHEMBL4165069 | 0.89 | PPARG (0.53) | FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL7243629 | 0.87 | PPARG (0.44) | FFAR1PPARGPPARAALDH1A1MEN1 | |
| SCHEMBL1130956 | 0.87 | FFAR1 (0.54) | FFAR1PPARGPPARAMEN1TP53 | |
| SCHEMBL6543635 | 0.86 | PPARG (0.49) | FFAR1PPARGPPARA | |
| SCHEMBL6543694 | 0.86 | PPARG (0.46) | FFAR1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL7242467 | 0.86 | PPARG (0.43) | FFAR1PPARGPPARAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569877-B2 | Benzimidazolyl phenyl anticancer agents | SANKYO COMPANY, LIMITED (JP) | 2003-05-27 | — | — | US | claimed |
| US-20020137776-A1 | Therapeutic and prophylactic agents for neoplasms | SANKYO COMPANY, LIMITED (JP) | 2002-09-26 | — | — | US | claimed |
| EP-1197211-A1 | PREVENTIVE AND THERAPEUTIC AGENTS FOR CANCER | Sankyo Company, Limited (JP) | 2002-04-17 | — | — | EP | claimed |
| US-6569877-B2 | Benzimidazolyl phenyl anticancer agents | SANKYO COMPANY, LIMITED (JP) | 2003-05-27 | — | — | US | disclosed |
| US-20020137776-A1 | Therapeutic and prophylactic agents for neoplasms | SANKYO COMPANY, LIMITED (JP) | 2002-09-26 | — | — | US | disclosed |
| EP-1197211-A1 | PREVENTIVE AND THERAPEUTIC AGENTS FOR CANCER | Sankyo Company, Limited (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137776-A1 | Therapeutic and prophylactic agents for neoplasms | VHL, TP53, BRCA1 | FFAR1 4874/4885PPARG 1300/4885PPARA 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.