Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.43 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253223 | 0.92 | F2 (0.58) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7246868 | 0.92 | F2 (0.57) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL6776785 | 0.91 | F2 (0.63) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7245225 | 0.87 | F2 (0.59) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6780972 | 0.86 | F2 (0.54) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7246239 | 0.81 | ITK (0.46) | F2ITK | |
| SCHEMBL7252982 | 0.79 | F2 (0.68) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7250157 | 0.78 | F2 (0.65) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7251642 | 0.78 | F2 (0.67) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL6779988 | 0.78 | F2 (0.71) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |