SCHEMBL7244694

SCHEMBL7244694

CC(C)(C)c1cc(CCC(=O)NCCCCCCCCNC(=O)CCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.79
KMT2A Q03164 3/20 0.79
MEN1 O00255 2/20 0.62
MAOB P27338 3/20 0.55
MAOA P21397 2/20 0.55
ACHE P22303 1/20 0.55
GSK3B P49841 2/20 0.51
PYGL P06737 1/20 0.50
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
AGTR1 P30556 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11257157 1.00 GAA (0.79) GAAKMT2AMEN1MAOBMAOA
SCHEMBL11667488 1.00 GAA (0.79) GAAKMT2AMEN1MAOBMAOA
SCHEMBL77798 1.00 GAA (0.79) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9008415 0.99 GAA (0.77) GAAKMT2AMEN1MAOBMAOA
SCHEMBL1149604 0.98 GAA (0.81) GAAKMT2AMEN1MAOBMAOA
SCHEMBL21984935 0.96 GAA (0.73) GAAKMT2AMEN1MAOBMAOA
SCHEMBL76483 0.95 GAA (0.81) GAAKMT2AMEN1MAOBMAOA
SCHEMBL19766466 0.95 GAA (0.71) GAAKMT2AMEN1MAOBMAOA
SCHEMBL19634869 0.95 GAA (0.80) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9898391 0.95 GAA (0.80) GAAKMT2AMEN1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218093-A1 POLYOLEFIN POLYMER INCORPORATING HINDERED PHENOL AND MANUFACTURE THEREOF ADVANCED POLYOLEFIN TECHNOLOGIES LLC 2024-07-04 US disclosed
US-20240218093-A1 POLYOLEFIN POLYMER INCORPORATING HINDERED PHENOL AND MANUFACTURE THEREOF ADVANCED POLYOLEFIN TECHNOLOGIES LLC 2024-07-04 US disclosed
US-20180148612-A1 STABILIZATION OF HOT MELT ADHESIVES BASF SE (DE) 2018-05-31 US disclosed
US-20180030244-A1 Alternative Methods to Control Crosslinking in High Impact Polystyrene FINA TECHNOLOGY (US) 2018-02-01 US disclosed
US-20180030244-A1 Alternative Methods to Control Crosslinking in High Impact Polystyrene FINA TECHNOLOGY (US) 2018-02-01 US disclosed
US-9809699-B2 Alternative methods to control crosslinking in high impact polystyrene FINA TECHNOLOGY, INC. (US) 2017-11-07 US disclosed
US-20170121501-A1 ALTERNATIVE METHODS TO CONTROL CROSSLINKING IN HIGH IMPACT POLYSTYRENE FINA TECHNOLOGY, INC. 2017-05-04 US disclosed
EP-1465955-B1 Method of elevating the auto-ignition temperature of inorganic oxide particulate GRACE GMBH & CO KG (DE) 2015-09-09 EP disclosed
US-8512604-B2 Photochromic coating exhibiting improved performance and reduced yellowness ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2013-08-20 US disclosed
US-8410197-B2 Inorganic oxide particulate comprising at least 10% by weight organic material; the particulate at a given volume has an auto-ignition temperature which is at least 20 degrees C. higher than that of a base particulate W. R. GRACE & CO. -CONN. (US) 2013-04-02 US disclosed
US-20110115108-A1 PHOTOCHROMIC COATING EXHIBITING IMPROVED PERFORMANCE AND REDUCED YELLOWNESS ESSILOR INTERNATIONAL (FR) 2011-05-19 US disclosed
US-20030060554-A1 Organic-containing particulate having elevated auto-ignition temperatures GRACE GMBH & CO. KG. (DE) 2003-03-27 US disclosed
US-4228297-A Process for the production of hydroxyalkylphenyl derivatives CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed