Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245849 | 1.00 | F2 (0.60) | F2NR1I2ADORA3SLC6A2AGTR1 | |
| SCHEMBL7249444 | 0.86 | F2 (0.64) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7249442 | 0.86 | F2 (0.64) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL505919 | 0.82 | F2 (0.84) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL6778976 | 0.81 | F2 (0.82) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7251541 | 0.81 | F2 (0.81) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7245914 | 0.80 | F2 (0.79) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL6785613 | 0.79 | F2 (0.72) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL6775032 | 0.78 | F2 (0.72) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL6780267 | 0.78 | F2 (0.81) | F2SLC22A2F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |