Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622732 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL4623641 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL4621452 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL7246945 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL7252510 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL2221666 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL7252140 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL4623766 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL7252807 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E | |
| SCHEMBL4622710 | 1.00 | TTR (0.60) | TTRFDPSACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |