Chlorotriphenylmethane

Chlorotriphenylmethane

SCHEMBL7246540

C.ClC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
CYP1A2 P05177 2/20 0.48
KCNN4 O15554 4/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP19A1 P11511 2/20 0.41
MAPK1 P28482 1/20 0.39
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
PTPN1 P18031 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorotriphenylmethane SCHEMBL28051494 0.97 TSHR (0.58) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL461 0.97 TSHR (0.65) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL16781670 0.97 TSHR (0.65) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL28253307 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL29446246 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL27386873 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL113884 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL7567317 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL11237663 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1
Chlorotriphenylmethane SCHEMBL27845684 0.93 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103443095-B Prepare the method for zidovudine and intermediate thereof SHANGHAI DESANO PHARMACEUTICALS INVESTMENT Co.,Ltd. (CN) 2016-01-20 CN claimed
CN-103201278-B Process for preparing zidovudine and intermediates thereof SHANGHAI DESANO PHARMACEUTICALS INVESTMENT Co.,Ltd. (CN) 2016-01-20 CN claimed
CN-102030805-B Theasapogenol derivative with anti-tumour activity and preparing method and application thereof UNIV SOUTH CHINA TECH 2012-08-22 CN claimed
CN-102030805-A Theasapogenol derivative with anti-tumour activity and preparing method and application thereof UNIV SOUTH CHINA TECH 2011-04-27 CN claimed
CN-108864192-A Function modified oligonucleotides and its subunit 萨勒普塔医疗公司 2018-11-23 CN disclosed
CN-103201278-B Process for preparing zidovudine and intermediates thereof SHANGHAI DESANO PHARMACEUTICALS INVESTMENT Co.,Ltd. (CN) 2016-01-20 CN disclosed
CN-103443095-B Prepare the method for zidovudine and intermediate thereof SHANGHAI DESANO PHARMACEUTICALS INVESTMENT Co.,Ltd. (CN) 2016-01-20 CN disclosed
US-20150189744-A1 THERMOSETTING RESIN COMPOSITION AND USAGE THEREOF SHENGYI TECHNOLOGY CO., LTD. (CN) 2015-07-02 US disclosed
CN-104039739-A Functionally modified oligonucleotides and subunits thereof SAREPTA THERAPEUTICS INC 2014-09-10 CN disclosed
CN-102030805-B Theasapogenol derivative with anti-tumour activity and preparing method and application thereof UNIV SOUTH CHINA TECH 2012-08-22 CN disclosed
CN-102030805-A Theasapogenol derivative with anti-tumour activity and preparing method and application thereof UNIV SOUTH CHINA TECH 2011-04-27 CN disclosed
US-6610708-B1 Anticoagulants SANKYO COMPANY, LIMITED (JP) 2003-08-26 US disclosed