Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756054 | 0.83 | AHR (0.57) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL15902404 | 0.81 | AHR (0.58) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL23664062 | 0.80 | AHR (0.50) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL15902322 | 0.79 | AHR (0.59) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL15902616 | 0.78 | AHR (0.55) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL1429044 | 0.78 | AHR (0.55) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11625297 | 0.76 | AKR1C2 (0.52) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL7835663 | 0.76 | AHR (0.53) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7835647 | 0.76 | AHR (0.53) | AHRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7823203 | 0.75 | AHR (0.52) | AHRALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030119022-A1 | Recognition and cleavage at the DNA major groove | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-26 | — | — | US | disclosed |