Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673796 | 0.90 | MAPT (0.57) | MAPTPLA2G1BATG4BHTTMEN1 | |
| SCHEMBL4678921 | 0.81 | MAPT (0.70) | MAPTPLA2G1BATG4BHTTMEN1 | |
| Hydrochloric Acid SCHEMBL7084627 | 0.81 | MAPT (0.54) | MAPTHTTKMT2AALDH1A1MAPK1 | |
| SCHEMBL7353785 | 0.81 | HSD17B10 (0.62) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL16208454 | 0.79 | KCNH2 (0.64) | MAPTPLA2G1BATG4BHTTMEN1 | |
| SCHEMBL19246210 | 0.79 | MAPT (0.68) | MAPTPLA2G1BATG4BHTTMEN1 | |
| SCHEMBL28307940 | 0.79 | MAPT (0.63) | MAPTALDH1A1LMNA | |
| SCHEMBL944312 | 0.78 | POLB (0.72) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2449511 | 0.78 | SMN1; SMN2 (0.50) | MAPTHTTALDH1A1GAA | |
| SCHEMBL10492889 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | SQLE, CYP17A1, ACOX1 | MAPT 4824/4885PLA2G1B 688/4885ATG4B 3879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.