Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252399 | 1.00 | MEN1 (0.45) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL4394009 | 0.98 | TSHR (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL4396265 | 0.95 | MEN1 (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7045822 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7043779 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7045692 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7045534 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7044912 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7045509 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7044520 | 0.93 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602825-B1 | Cyclization of an isocyanate with a thiourea and carbonic acid | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-05 | — | — | US | disclosed |