SCHEMBL725063

SCHEMBL725063

c1cc(Nc2ccncc2)ccn1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.70
CTSD P07339 1/20 0.65
MDM2 Q00987 1/20 0.50
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.45
ADRA2A P08913 2/20 0.45
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45
ADRA1A P35348 1/20 0.45
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
KCNH2 Q12809 1/20 0.42
ACVRL1 P37023 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1720986 0.88 HSD17B10 (0.67) RAD52CTSDMAPTADRA2AADRA2B
SCHEMBL10570649 0.84 KMT2A (0.61) RAD52CTSDMAPTLMNAADRA2A
SCHEMBL11479808 0.84 RAD52 (0.60) RAD52CTSDMAPTLMNAPOLB
SCHEMBL8236630 0.84 RAD52 (0.60) RAD52CTSDMAPTKDM4EL3MBTL1
SCHEMBL12240924 0.84 RAD52 (0.60) RAD52CTSDMDM2MAPTPOLB
SCHEMBL7335999 0.84 RAD52 (0.60) RAD52CTSDMDM2MAPTLMNA
SCHEMBL10569084 0.84 MEN1 (0.61) RAD52CTSDMAPTLMNAPOLB
SCHEMBL147419 0.84 RAD52 (0.54) RAD52CTSDMDM2MAPTLMNA
SCHEMBL2086928 0.84 RAD52 (1.00) RAD52CTSDMAPTLMNAPOLB
SCHEMBL21012394 0.82 MAPT (0.61) RAD52CTSDMAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955116-A Metal organic framework material taking multiphase hindered Lewis acid-base pair as catalytic site, preparation and catalytic application 大连理工大学 2025-05-09 CN claimed
CN-118930878-A Metal organic frame material with ethylene and propylene adsorption separation function and preparation method thereof 西北大学 2024-11-12 CN claimed
CN-116272259-B Desulfurization and decarbonization solvent suitable for low-pressure gas and application thereof 四川精事达科技有限公司 2024-02-13 CN claimed
CN-116574052-A Lead-based perovskite material with second-order nonlinear optical effect, preparation method and application 江西师范大学 2023-08-11 CN claimed
CN-113019330-B Preparation of copper-based metal-organic framework material and acetylene/carbon dioxide separation application thereof 北京工业大学 2023-07-28 CN claimed
CN-116272259-A Desulfurization and decarbonization solvent suitable for low-pressure gas and application thereof 四川精事达科技有限公司 2023-06-23 CN claimed
CN-114184789-B Prostate specific antigen detection probe and kit for detecting prostate specific antigen 云南大学 2023-06-16 CN claimed
CN-108699019-B Benzofuran derivatives useful in the treatment of central nervous system and other diseases 华纳巴布科克绿色化学学院有限公司 2022-05-10 CN claimed
CN-114184789-A Prostate specific antigen detection probe and prostate specific antigen detection kit 云南大学 2022-03-15 CN claimed
CN-113019330-A Preparation of copper-based metal-organic framework material and acetylene/carbon dioxide separation application thereof 北京工业大学 2021-06-25 CN claimed
CN-111146457-B Preparation and application of porous composite material electrocatalyst based on bimetallic macrocyclic compound 大连理工大学 2021-05-04 CN claimed
CN-112062781-A Crystal structure of copper complex and magnetic property thereof 桂林理工大学 2020-12-11 CN claimed
CN-107674212-B One-dimensional spin cross molecular magnetic material and preparation method thereof 山东理工大学 2020-07-28 CN claimed
CN-111146457-A Preparation and application of porous composite material electrocatalyst based on bimetallic macrocyclic compound 大连理工大学 2020-05-12 CN claimed
US-10087289-B2 Monomers, oligomeric complexes, coordination polymers, and methods for their preparation and use EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-10-02 US claimed
US-20140121349-A1 MONOMERS, OLIGOMERIC COMPLEXES, COORDINATION POLYMERS, AND METHODS FOR THEIR PREPARATION AND USE EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2014-05-01 US claimed
US-20120214962-A1 Monomers, Oligomeric Complexes, Coordination Polymers, and Methods for Their Preparation and Use EMPIRE TECHNOLOGY DEVELOPMENT LLC 2012-08-23 US claimed
EP-2136829-A1 KINASE PROTEIN BINDING INHIBITORS University Of Florida Research Foundation (US) 2009-12-30 EP claimed
US-20090239850-A1 Kinase protein binding inhibitors UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2009-09-24 US claimed
WO-2008115443-A1 KINASE PROTEIN BINDING INHIBITORS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2008-09-25 WO claimed