SCHEMBL7250964

SCHEMBL7250964

Nc1[c]ncnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28561507 0.70
SCHEMBL3706164 0.70
SCHEMBL2287334 0.70
SCHEMBL16440003 0.65
SCHEMBL16439892 0.65
SCHEMBL41301 0.64
SCHEMBL3715188 0.60
SCHEMBL896620 0.60
SCHEMBL2066991 0.60
SCHEMBL19917172 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534512-B1 A therapeutic method is provided, employing an antiviral compound of the general formula: nucleosides which exhibit antiviral activity. REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-03-18 US disclosed
US-6072053-A ANTIVIRAL COMPOUND UNIV MINNESOTA (US) 2000-06-06 US disclosed
US-5962684-A Method of preparation of dideoxycarbocyclic nucleosides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-10-05 US disclosed
US-5922694-A SUBSTITUTED-OXY METHYL CYCLOPENTENYL-SUBSTITUTED PURINES AND 8-AZAPURINES ANTI HUMAN IMMUNODEFICIENCY VIRUS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-07-13 US disclosed
US-5763607-A VIRICIDES REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1998-06-09 US disclosed
US-5631370-A VIRICIDES FOR HUMAN T-CELL LEUKEMIA/LYMPHOMA REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1997-05-20 US disclosed
US-5567703-A Method for treating HIV infections with dideoxycarbocyclic nucleosides REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-10-22 US disclosed
US-5175292-A Viricides, aids REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-12-29 US disclosed
US-5122517-A Human t-cell leukemia/lymphoma viruses REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-06-16 US disclosed
EP-0346132-B1 PHARMACEUTICAL PRODUCTS THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1992-03-11 EP disclosed
US-4950758-A ANTIVIRAL AND ANTITUMOR AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-08-21 US disclosed
US-4931559-A VIRICIDES, ANTITUMOR AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-06-05 US disclosed
US-4916224-A VIRICIDES FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-04-10 US disclosed
EP-0346132-A1 Pharmaceutical products THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1989-12-13 EP disclosed
US-4704392-A VIRICIDES SYNTEX (U.S.A.) INC. (US) 1987-11-03 US disclosed
US-4605659-A HERPES; HEPATITUS SYNTEX (U.S.A.) INC. (US) 1986-08-12 US disclosed