Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598283 | 0.86 | TSHR (0.54) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL6599662 | 0.75 | CYP11B1 (0.52) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL7252343 | 0.73 | MAPK1 (0.40) | KMT2AMAPK1POLB | |
| SCHEMBL7165398 | 0.72 | POLB (0.63) | KMT2ALMNAMAPK1CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6598041 | 0.72 | TSHR (0.53) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL29907219 | 0.71 | CYP3A4 (0.65) | MAPTCMA1CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL49914 | 0.71 | CYP3A4 (0.65) | MAPTCMA1CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL2873266 | 0.71 | CYP3A4 (0.65) | MAPTCMA1CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL28330025 | 0.69 | TSHR (0.64) | KDM4ETSHRKMT2AMEN1MAPT | |
| Ethane SCHEMBL11863120 | 0.68 | CYP3A4 (0.61) | MAPTSMN1; SMN2CMA1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630593-B1 | A process for preparing a 1-substituted 5-hydroxymethylimidazole of the formula: wherein R represents alkyl, hydroxyalkyl, allyl, or substituted or unsubstituted arylmethyl or diarylmethyl, comprising the step of reacting a | LG CHEM INVESTMENT LTD. (KR) | 2003-10-07 | — | — | US | disclosed |