Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 18/20 | 0.77 |
| ▸ | F3 | P13726 | 7/20 | 0.77 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | PLAU | P00749 | 1/20 | 0.62 |
| ▸ | PLAT | P00750 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427056 | 0.91 | F7 (0.79) | F7F3KLKB1F2F10 | |
| SCHEMBL7253291 | 0.91 | F7 (0.78) | F7F3KLKB1F2F10 | |
| SCHEMBL7253477 | 0.88 | F7 (0.74) | F7F3KLKB1F2F10 | |
| SCHEMBL6389292 | 0.87 | F7 (1.00) | F7F3KLKB1F2F10 | |
| SCHEMBL7258122 | 0.85 | F7 (0.88) | F7F3KLKB1 | |
| SCHEMBL6395212 | 0.84 | F7 (0.70) | F7F3KLKB1F2F10 | |
| SCHEMBL6393294 | 0.82 | F3 (0.70) | F7F3KLKB1 | |
| SCHEMBL6428578 | 0.81 | F7 (0.64) | F7F3KLKB1F2F10 | |
| SCHEMBL7258358 | 0.77 | F7 (0.88) | F7F3KLKB1 | |
| SCHEMBL6395167 | 0.76 | F7 (0.87) | F7F3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006670-A2 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL]-SUCCINIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006670-A2 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL]-SUCCINIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |