Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.78 |
| ▸ | PTPRA | P18433 | 8/20 | 0.78 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.78 |
| ▸ | PTPRF | P10586 | 1/20 | 0.78 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504066 | 0.96 | PTPN1 (0.85) | PTPN1PTPRAPTPN2PTPRFPTPN22 | |
| SCHEMBL7117630 | 0.91 | PTPN1 (0.92) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL7259511 | 0.91 | PTPN1 (0.83) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL7254363 | 0.90 | PTPN1 (0.90) | PTPN1PTPRAPTPN2PTPRFPTPN22 | |
| SCHEMBL7050875 | 0.90 | PTPN1 (0.79) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL29384398 | 0.88 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRFPTPN22 | |
| SCHEMBL6500588 | 0.88 | PTPN1 (1.00) | PTPN1PTPRAPTPN2PTPRFPTPN22 | |
| SCHEMBL7519706 | 0.87 | PTPN1 (0.74) | PTPN1PTPRAPTPN2PTPRF | |
| SCHEMBL6504012 | 0.87 | PTPN1 (0.90) | PTPN1PTPRAPTPN2PTPRFPTPN22 | |
| SCHEMBL6500055 | 0.87 | PTPN1 (0.87) | PTPN1PTPRAPTPN2PTPRFPTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072537-A2 | SELECTIVE PROTEIN TYROSINE PHOSPHATATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-09-04 | — | — | WO | disclosed |