Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254165 | 0.78 | CYP2C9 (0.42) | CYP2C9CNR2CA2 | |
| SCHEMBL7253880 | 0.78 | CYP2C9 (0.40) | CYP2C9CNR2CA2 | |
| SCHEMBL7247683 | 0.78 | CYP2C9 (0.40) | CYP2C9CNR2CA2 | |
| SCHEMBL7250446 | 0.77 | CYP2C9 (0.39) | CYP2C9CNR2 | |
| SCHEMBL7249574 | 0.76 | CNR2 (0.45) | CYP2C9CNR2 | |
| SCHEMBL7252576 | 0.68 | — | — | |
| SCHEMBL7254428 | 0.67 | CNR2 (0.52) | CYP2C9CNR2 | |
| SCHEMBL5386084 | 0.67 | EPHX1 (0.39) | CYP2C9CNR2CA2CA1 | |
| SCHEMBL7249608 | 0.67 | PAOX (0.31) | — | |
| SCHEMBL5381166 | 0.66 | EPHX1 (0.38) | CYP2C9CNR2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545022-B1 | Treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammatory diseases, and gastrointestinal disorders | PFIZER INC. | 2003-04-08 | — | — | US | disclosed |