SCHEMBL725534

SCHEMBL725534

CC[C@H](c1cccc(N(C(C)C)C(C)C)c1)c1cc(C)ccc1OC(=O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.46
CHRM1 P11229 3/20 0.46
KMT2A Q03164 3/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
RECQL P46063 1/20 0.36
ALOX15 P16050 1/20 0.36
CHRM5 P08912 2/20 0.35
CHRM3 P20309 2/20 0.35
HRH1 P35367 2/20 0.35
ADRB2 P07550 2/20 0.35
CX3CR1 P49238 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724698 0.88 CHRM2 (0.45) CHRM2CHRM1POLBAPEX1GAA
SCHEMBL4659057 0.87 CHRM2 (0.62) CHRM2CHRM1KMT2APOLBAPEX1
SCHEMBL1158251 0.87 CHRM2 (0.62) CHRM2CHRM1KMT2APOLBAPEX1
SCHEMBL7754999 0.86 CHRM2 (0.51) CHRM2CHRM1KMT2APOLBAPEX1
Hydrochloric Acid SCHEMBL16166361 0.86 CHRM2 (0.61) CHRM2CHRM1KMT2APOLBAPEX1
SCHEMBL11301929 0.85 CHRM2 (0.43) CHRM2CHRM1KMT2AALOX15CTSA
SCHEMBL434110 0.85 TSHR (0.34) CHRM2CHRM1KMT2ANPSR1GAA
SCHEMBL4660350 0.80 CHRM2 (0.46) CHRM2CHRM1KMT2APOLBESR1
SCHEMBL16166441 0.79 CHRM2 (0.55) CHRM2CHRM1KMT2AALOX15ADRB2
SCHEMBL4412379 0.79 CHRM1 (0.54) CHRM2CHRM1KMT2ANPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025941-A2 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2012-03-01 WO disclosed